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Beta Galactosidase Monoclonal antibody, PBS Only

Beta Galactosidase Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66586-1-PBS

产品说明书

CloneNo. 4F4F4

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, rat

应用

WB, IHC, IF/ICC, Indirect ELISA

GLB1, 4F4F4, Acid beta-galactosidase, Beta-galactosidase, EBP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


产品信息

66586-1-PBS targets Beta Galactosidase in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 Beta Galactosidase fusion protein Ag8069 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 galactosidase, beta 1
别名 GLB1, 4F4F4, Acid beta-galactosidase, Beta-galactosidase, EBP
计算分子量 76 kDa
观测分子量 64-66 kDa, 76-85 kDa
GenBank蛋白编号BC007493
基因名称 GLB1/Beta-galactosidase
Gene ID (NCBI) 2720
RRIDAB_2881946
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein G purification
UNIPROT IDP16278
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

GLB1(Beta-galactosidase) is also named as ELNR1 or Lactase. It cleaves beta-linked terminal galactosyl residues from gangliosides, glycoproteins, and glycosaminoglycans. This protein is identical to the elastin-binding protein (EBP), a major component of the nonintegrin cell surface receptor complex expressed in fibroblasts, smooth muscle cells, chondroblasts, leukocytes, and certain cancer cell types. Defects in GLB1 are the cause of GM1-gangliosidosis type 1 (GM1G1), GM1-gangliosidosis type 2 (GM1G2), GM1-gangliosidosis type 3 (GM1G3) and mucopolysaccharidosis type 4B (MPS4B). GBL1 is synthesized as an 85-kDa precursor that is C-terminally processed into a 64-66 kDa mature form and the released ~20-kDa proteolytic fragment was thought to be degraded (PMID: 10744681). GLB1 has 3 isoforms with MW of 76 kDa, 73 kda and 61 kDa.

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