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Bidisomide

Bidisomide (SC40230) (SC40230) 属于 I 类抗心律失常剂。

CAS号

116078-65-0

分子式

C22H34ClN3O2

主要靶点

Others

仅限科研使用

Cat No : CM18286

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Synonyms

SC40230

验证数据展示

  • CAS No.: 116078-65-0

    Bidisomide
    CAS#: 116078-65-0

产品信息

Bidisomide is an agent of class I antiarrhythmic.

CAS号 116078-65-0
分子式 C22H34ClN3O2
主要靶点 Others
主要通路 其他
分子量 407.98
纯度 99.56%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 SC40230

体内活性

Bidisomide's anti-arrhythmia effects. Bidisomide (5 mg/kg) reduces the number of premature ventricular complexes and the incidence of ventricular tachycardia and ventricular fibrillation similarly to Mexiletine (MXT) and Disopyramide (DSP) in rats with ventricular arrhythmias induced by coronary artery occlusion. After 5 minutes of coronary artery occlusion, the antiarrhythmic effect of 5 mg/kg Bidisomide was similar to the same dose of MXT and DSP in rats with ventricular arrhythmias caused by coronary reperfusion. All three drugs significantly slow the heart rate[1].

溶解度

DMSO:225.0 mg/mL (551.5 mM),Sonification is recommended.

参考文献

1.Komori S, et al. Effects of bidisomide (SC-40230), a new class I antiarrhythmic agent, on ventricular arrhythmias induced by coronary artery occlusion and reperfusion in anesthetized rats; comparison with mexiletine and disopyramide. Heart Vessels. 1995;10(1):7-11.

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

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