• 产品信息

Boc-NH-PEG11-OH

Boc-NH-PEG11-OH 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。

CAS号

1556847-53-0

分子式

C27H55NO13

主要靶点

Others|PROTAC Linker

仅限科研使用

Cat No : CM15329

Print datasheet

Synonyms

叔丁氧羰基十一聚乙二醇羟基



产品信息

Boc-NH-PEG11-OH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

CAS号 1556847-53-0
分子式 C27H55NO13
主要靶点 Others|PROTAC Linker
主要通路 其他|PROTAC
分子量 601.72
纯度 98.08%, 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 叔丁氧羰基十一聚乙二醇羟基

体外活性

PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

参考文献

1.An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2