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Bromfenac Sodium

Bromfenac Sodium (AHR 10282R) 是可口服的COX 抑制剂，抑制COX-1和COX-2的IC50值分别为 5.56 和 7.45 nM。它是溴化非甾体类抗炎药，通常用于白内障的术后炎症和疼痛以及假晶状体囊状黄斑水肿的研究。

CAS号

91714-93-1

分子式

C15H11BrNO3·Na

主要靶点

COX

仅限科研使用

Cat No : CM03534

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Synonyms

AHR 10282B|溴芬酸钠|AHR 10282R|Bronuck

验证数据展示

  • CAS No.: 91714-93-1

    Bromfenac Sodium
    CAS#: 91714-93-1

产品信息

Bromfenac Sodium (AHR 10282R) is a nonsteroidal anti-inflammatory drug (NSAID), which has anti-inflammatory activity and may block prostaglandin synthesis by inhibiting cyclooxygenase 1 and 2.

CAS号 91714-93-1
分子式 C15H11BrNO3·Na
主要靶点 COX
主要通路 免疫与炎症|神经科学
分子量 356.15
纯度 99.22%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 AHR 10282B|溴芬酸钠|AHR 10282R|Bronuck

靶点活性

COX-2:7.45 nM (IC50)|COX-1:5.56 nM (IC50)

溶解度

DMSO:66 mg/mL (185.3 mM),H2O:65 mg/mL (182.5 mM),Ethanol:2 mg/mL (5.61 mM)

参考文献

1.Sancilio LF, et al. Arzneimittelforschung, 1987, 37(5), 513-519.
2.Kirkman SK, et al. Drug Metab Dispos, 1998, 26(7), 720-723.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
=
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2