验证数据展示
经过测试的应用
| Positive WB detected in | A549 cells, DU 145 cells, SK-BR-3 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
20876-1-AP targets C17orf37 in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | C17orf37 fusion protein Ag14975 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | chromosome 17 open reading frame 37 |
| 别名 | ORB3, Migration and invasion enhancer 1, MIEN1, HBV X-transactivated gene 4 protein, HBV XAg-transactivated protein 4 |
| 计算分子量 | 115 aa, 12 kDa |
| 观测分子量 | 12 kDa |
| GenBank蛋白编号 | BC006006 |
| 基因名称 | C17orf37 |
| Gene ID (NCBI) | 84299 |
| RRID | AB_3085626 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q9BRT3 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
C17orf37 (chromosome 17 open reading frame 37), also known as C35/Rdx12/MGC14832, is located on human chromosome 17q12, 505 nucleotides from the 3¶ end of the ERBB2 oncogenes. C17orf37 expression positively correlates with grade and stage of breast cancer, and increased expression has been shown in prostate cancer cells and tissue specimens (PMID: 17121940, 19503095)..C17orf37 gene encodes a 12-kDa protein that does not have sequence similarity with any known protein. C17orf37 is expressed as a cytosolic protein with predominant membrane localization (PMID: 21628459).
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for C17orf37 antibody 20876-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |