C4orf14 Polyclonal antibody

C4orf14 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 20323-1-AP

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Synonyms

C4orf14, hAtNOS1, mAtNOS1, NOA1



产品信息

The immunogen of 20323-1-AP is C4orf14 Fusion Protein expressed in E. coli.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen C4orf14 fusion protein Ag14186 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name chromosome 4 open reading frame 14
Synonyms C4orf14, hAtNOS1, mAtNOS1, NOA1
Calculated Molecular Weight 698 aa, 78 kDa
GenBank Accession NumberBC004894
Gene Symbol C4orf14
Gene ID (NCBI) 84273
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ8NC60
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Nitric oxide associated-1 (NOA1), also known as C4orf14, is an evolutionarily conserved guanosine triphosphate (GTP) binding protein. It localizes predominantly to mitochondria in mammalian cells. Human NOA1 has been shown to interact with complex I of the electron transport chain and with three mitoribosomal proteins, MRPL12, MRPS27, and MRPS29, indicating that NOA1 may interact with the mitoribosome. Recent studies suggest that C4orf14 interacts with human mitochondrial nucleoids, and is involved in the biogenesis of the small mitochondrial ribosomal subunit.