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Conjugate
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C6 Polyclonal antibody, PBS Only

C6 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

WB, IHC, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 17239-1-PBS

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Synonyms

验证数据展示

  • WB analysis of human blood using 17239-1-AP (same clone as 17239-1-PBS)

    WB analysis of human blood using 17239-1-AP (same clone as 17239-1-PBS)

    human blood were subjected to SDS PAGE followed by western blot with 17239-1-AP (C6 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

  • IP experiment of human plasma using 17239-1-AP (same clone as 17239-1-PBS)

    IP experiment of human plasma using 17239-1-AP (same clone as 17239-1-PBS)

    IP result of anti-C6 (IP:17239-1-AP, 4ug; Detection:17239-1-AP 1:800) with human plasma lysate 4000ug. This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse liver using 17239-1-AP (same clone as 17239-1-PBS)

    IHC staining of mouse liver using 17239-1-AP (same clone as 17239-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17239-1-AP (C6 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse liver using 17239-1-AP (same clone as 17239-1-PBS)

    IHC staining of mouse liver using 17239-1-AP (same clone as 17239-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse liver tissue slide using 17239-1-AP (C6 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17239-1-PBS in a different storage buffer formulation.

产品信息

17239-1-PBS targets C6 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.

Tested Applications WB, IHC, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse
Immunogen C6 fusion protein Ag11083 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name complement component 6
Synonyms
Calculated Molecular Weight 934 aa, 105 kDa
Observed Molecular Weight 105 kDa
GenBank Accession NumberBC035723
Gene Symbol C6
Gene ID (NCBI) 729
RRIDAB_2878366
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP13671
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

The final consequence of complement activation is formation of the membrane attack complex (MAC), a multiprotein assembly that perforates cell membranes, forming transmembrane channels. C6 is 1 of 5 late-acting proteins of complement that participate in assembly and function of the MAC. The deduced C6 protein contains 934 amino acids, including a 21-amino acid N-terminal signal sequence and 2 N-glycosylation sites. Mutations in the C6 gene are associated with complement component-6 deficiency.