验证数据展示
发表文章中的应用
| WB | See 5 publications below |
| IF | See 1 publications below |
产品信息
15443-1-AP targets CaMKII Delta in WB, IF, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | WB, IF |
| 经测试反应性 | human, mouse, rat |
| 文献引用反应性 | mouse, rat |
| 免疫原 | CaMKII Delta fusion protein Ag7323 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | calcium/calmodulin-dependent protein kinase II delta |
| 别名 | CaM kinase II subunit delta, CaMK II subunit delta, CAMK2D, CAMKD, CaMKII delta |
| 计算分子量 | 59 kDa |
| 观测分子量 | 64 kDa |
| GenBank蛋白编号 | BC032784 |
| 基因名称 | CAMK2D |
| Gene ID (NCBI) | 817 |
| RRID | AB_2068087 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | Q13557 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CaMKII delta, also named as CAMKD and CaMKII delta, belongs to the protein kinase superfamily, CAMK Ser/Thr protein kinase family and CaMK subfamily. CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release, composed of four different chains: alpha, beta, gamma, and delta. The CAMK2 protein kinases contain a unique C-terminal subunit association domain responsible for oligomerization. The different chains assemble into homo-or heteromultimeric holoenzymes composed of 8 to 12 subunits. This antibody may have cross reaction with CAMK2A/B/G due to the high homology.
发表文章
| Species | Application | Title |
|---|---|---|
Cell Calcium Activation of transient receptor potential vanilloid 4 exacerbates myocardial ischemia-reperfusion injury via JNK-CaMKII phosphorylation pathway in isolated mice hearts. | ||
Life Sci Chronic stimulation of the sigma-1 receptor ameliorates ventricular ionic and structural remodeling in a rodent model of depression. | ||
Mol Cell Biochem Pleiotropic, non-cell death-associated effects of inhibitors of receptor-interacting protein kinase 1 in the heart. | ||