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  • Featured Product
  • KD/KO Validated

CAPG-Specific Polyclonal antibody, PBS Only

CAPG-Specific Polyclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 19535-1-PBS

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Synonyms

验证数据展示

  • WB analysis of mouse lung using 19535-1-AP (same clone as 19535-1-PBS)

    WB analysis of mouse lung using 19535-1-AP (same clone as 19535-1-PBS)

    mouse lung tissue were subjected to SDS PAGE followed by western blot with 19535-1-AP (CAPG-Specific antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

  • IHC staining of human spleen using 19535-1-AP (same clone as 19535-1-PBS)

    IHC staining of human spleen using 19535-1-AP (same clone as 19535-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human spleen using 19535-1-AP (CAPG-Specific antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

  • IHC staining of human spleen using 19535-1-AP (same clone as 19535-1-PBS)

    IHC staining of human spleen using 19535-1-AP (same clone as 19535-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human spleen using 19535-1-AP (CAPG-Specific antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 19535-1-PBS in a different storage buffer formulation.

产品信息

19535-1-PBS targets CAPG-Specific in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name capping protein (actin filament), gelsolin-like
Synonyms
Calculated Molecular Weight 39 kDa
Observed Molecular Weight 43 kDa
GenBank Accession NumberNM_001747
Gene Symbol CAPG
Gene ID (NCBI) 822
RRIDAB_10638618
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP40121
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CapG (gelsolin-like actin-capping protein) is a member of the gelsolin superfamily proteins, which regulates actin filament length by capping or severing filaments. Studies have shown a role for CapG in regulating cell motility. The expression of CapG is upregulated under hypoxia and in turn increases the motility of cells. Recently it has been reported that the overexpression of CapG is associated with the progression of lung adenocarcinoma as well as lyphatic invasion status of cholangiocarcinoma, which may be used for prognosis of these tumors.(21908955,22155129)