• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
  • Featured Product
  • KD/KO Validated

CCAR2 Monoclonal antibody, PBS Only

CCAR2 Monoclonal Antibody for WB, IF, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human, pig

Applications

WB, IF, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2D10F8

Cat No : 66497-1-PBS

Print datasheet

Synonyms

CCAR2, cell cycle and apoptosis regulator 2, DBC 1, DBC.1, DBC1, KIAA1967, p30 DBC, Protein KIAA1967

验证数据展示

  • WB analysis using 66497-1-Ig (same clone as 66497-1-PBS)

    WB analysis using 66497-1-Ig (same clone as 66497-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66497-1-Ig (CCAR2 antibody) at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66497-1-PBS in a different storage buffer formulation.

  • WB analysis of HEK-293 using 66497-1-Ig (same clone as 66497-1-PBS)

    WB analysis of HEK-293 using 66497-1-Ig (same clone as 66497-1-PBS)

    WB result of CCAR2 antibody (66497-1-Ig; 1:2000; incubated at room temperature for 1.5 hours) with sh-Control and sh-CCAR2 transfected HEK-293 cells. This data was developed using the same antibody clone with 66497-1-PBS in a different storage buffer formulation.

  • IHC staining of human cervical cancer using 66497-1-Ig (same clone as 66497-1-PBS)

    IHC staining of human cervical cancer using 66497-1-Ig (same clone as 66497-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 66497-1-Ig (CCAR2 antibody) at dilution of 1:500 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66497-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with DBC1/CCAR2 antibody included
  • IHC staining of human cervical cancer using 66497-1-Ig (same clone as 66497-1-PBS)

    IHC staining of human cervical cancer using 66497-1-Ig (same clone as 66497-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human cervical cancer tissue slide using 66497-1-Ig (CCAR2 antibody) at dilution of 1:500 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66497-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with DBC1/CCAR2 antibody included
  • IF Staining of HeLa using 66497-1-Ig (same clone as 66497-1-PBS)

    IF Staining of HeLa using 66497-1-Ig (same clone as 66497-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HeLa cells using 66497-1-Ig (CCAR2 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66497-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy DBC1/CCAR2 Ready-To-Use IHC Kit. DBC1/CCAR2 primary antibody included.

产品信息

66497-1-PBS targets CCAR2 in WB, IF, IHC, Indirect ELISA applications and shows reactivity with Human, pig samples.

Tested Applications WB, IF, IHC, Indirect ELISA Application Description
Tested Reactivity Human, pig
Immunogen CCAR2 fusion protein Ag18374 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name KIAA1967
Synonyms CCAR2, cell cycle and apoptosis regulator 2, DBC 1, DBC.1, DBC1, KIAA1967, p30 DBC, Protein KIAA1967
Calculated Molecular Weight 923 aa, 103 kDa
Observed Molecular Weight 130 kDa
GenBank Accession NumberBC018269
Gene Symbol KIAA1967
Gene ID (NCBI) 57805
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ8N163
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

Cell cycle and apoptosis regulator protein 2 (CCAR2), previously known as DBC1/KIAA1967, regulates diverse cellular functions including transcription, mRNA splicing, metabolism, and circadian cycle. CCAR2 is a critical regulator of cell death or survival following cellular stresses. CCAR2 is a widely expressed protein involved in the regulation of a variety of transcriptional complexes. High expression of CCAR2 correlates with poor outcomes in many human tumor types such as squamous cell carcinoma (SCC).