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CCBE1 Polyclonal antibody

CCBE1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 24449-1-AP

Print datasheet

Synonyms

CCBE1, Full of fluid protein homolog, KIAA1983

验证数据展示

  • IHC staining of human kidney using 24449-1-AP

    IHC staining of human kidney using 24449-1-AP

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 24449-1-AP (CCBE1 Antibody) at dilution of 1:200 (under 10x lens).

  • IHC staining of human kidney using 24449-1-AP

    IHC staining of human kidney using 24449-1-AP

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 24449-1-AP (CCBE1 Antibody) at dilution of 1:200 (under 40x lens).

经过测试的应用

Positive IHC detected inhuman kidney tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

The immunogen of 24449-1-AP is CCBE1 Fusion Protein expressed in E. coli.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen CCBE1 fusion protein Ag19686 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name collagen and calcium binding EGF domains 1
Synonyms CCBE1, Full of fluid protein homolog, KIAA1983
Calculated Molecular Weight 406 aa, 44 kDa
GenBank Accession NumberBC046645
Gene Symbol CCBE1
Gene ID (NCBI) 147372
RRIDAB_2879553
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ6UXH8
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CCBE1 (collagen and calcium-binding EGF domain-containing protein 1) is a secreted protein that is indispensible for lymphangiogenesis during development. CCBE1 may be a guidance molecule that regulates lymphangioblast budding and possibly migration (PMID: 19287381). The gene of CCBE1 maps to 18q21.32 and encodes a protein of 44 kDa that contains an EGF-like domain and two collagen-like domains. Mutations in the CCBE1 gene cause Hennekam lymphangiectasia-lymphedema syndrome (PMID: 19935664).

实验方案

Product Specific Protocols
IHC protocol for CCBE1 antibody 24449-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols