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验证数据展示

  • IF Staining of U2OS using 82998-4-RR (same clone as 82998-4-PBS)

    IF Staining of U2OS using 82998-4-RR (same clone as 82998-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using CCDC23 antibody (82998-4-RR, Clone: 230175B2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1).CL594-Phalloidin (red). This data was developed using the same antibody clone with 82998-4-PBS in a different storage buffer formulation.

  • IF Staining of U2OS using 82998-4-RR (same clone as 82998-4-PBS)

    IF Staining of U2OS using 82998-4-RR (same clone as 82998-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using CCDC23 antibody (82998-4-RR, Clone: 230175B2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Mouse IgG(H+L) (SA00013-1).CL594-Phalloidin (red). This data was developed using the same antibody clone with 82998-4-PBS in a different storage buffer formulation.

CCDC23 Recombinant antibody, PBS Only

CCDC23 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA
Cat No. 82998-4-PBS

产品说明书

CloneNo. 230175B2

宿主/亚型

Rabbit / IgG

种属反应性

Human

应用

IF/ICC, Indirect ELISA

别名

CCDC23, SVBP

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

82998-4-PBS targets CCDC23 in IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.

经测试应用 IF/ICC, Indirect ELISA Application Description
经测试反应性 Human
免疫原 CCDC23 fusion protein Ag33650 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 coiled-coil domain containing 23
别名 CCDC23, SVBP
GenBank蛋白编号BC029427
基因名称 CCDC23
Gene ID (NCBI) 374969
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ8N300
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CCDC23 also known as SVBP is a small vasohibin-binding protein of 66 amino acids, and functions as a chaperone of VASH1 in vascular endothelial cells(PMID: 20736312). SVBP enhances the tyrosine carboxypeptidase activity of VASH1 and VASH2, thereby promoting the removal of the C-terminal tyrosine residue of alpha-tubulin(PMID: 29146869, 31171830). Mutations in SVBP cause Neurodevelopmental disorders with ataxia, hypotonia, and microcephaly (NEDAHM)(PMID: 30607023, 31363758).