验证数据展示
经过测试的应用
Positive WB detected in | PMA, LPS and Brefeldin A treated THP-1 cells |
推荐稀释比
Application | Dilution |
---|---|
Western Blot (WB) | WB : 1:500-1:2000 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
12859-1-AP targets CCL3L1 in WB, ELISA applications and shows reactivity with human samples.
Tested Applications | WB, ELISA Application Description |
Tested Reactivity | human |
Immunogen | CCL3L1 fusion protein Ag3891 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | chemokine (C-C motif) ligand 3-like 1 |
Synonyms | 464.2, C C motif chemokine 3 like 1, CCL3L1, CCL3L3, D17S1718, G0S19 2, LD78, LD78 beta(1 70), LD78BETA, MIP1AP, PAT 464.2, SCYA3L, SCYA3L1 |
Calculated Molecular Weight | 10 kDa |
Observed Molecular Weight | 10 kDa |
GenBank Accession Number | BC027888 |
Gene Symbol | CCL3L1 |
Gene ID (NCBI) | 6349 |
RRID | AB_3085401 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P16619 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CCL3L1 is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility.
实验方案
Product Specific Protocols | |
---|---|
WB protocol for CCL3L1 antibody 12859-1-AP | Download protocol |
Standard Protocols | |
---|---|
Click here to view our Standard Protocols |