CD100 Recombinant antibody, PBS Only
CD100 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
WB, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
241709G4
验证数据展示
产品信息
84465-5-PBS targets CD100 in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | human |
| Immunogen | Recombinant Protein 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| Synonyms | |
| Calculated Molecular Weight | 96 kDa |
| Observed Molecular Weight | 150 kDa |
| GenBank Accession Number | BC054500 |
| Gene Symbol | SEMA4D/CD100 |
| Gene ID (NCBI) | 10507 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purfication |
| UNIPROT ID | Q92854 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD100 (also known as SEMA4D), a 150 kDa homodimer, belongs to the family of immune semaphorins, and CD100 is abundantly expressed on resting T cells, NK cells, and antigen-presenting cells. As a transmembrane glycoprotein, it is digested to its soluble form, sCD100, by specific matrix metalloproteinases. CD100 has been reported that the expression levels of CD100, and one of its receptors, plexin-B1 (PLXNB1), are increased in head and neck, prostate, colon, breast, and lung cancers, and the interaction between them provides oncogenic signaling essential for tumor growth and metastasis.