Anti-Human CD11a (TS2/4) Mouse IgG1 Recombinant Antibody, PBS Only
CD11a Uni-rAbTM Recombinant Antibody for FC
Host / Isotype
Mouse / IgG1
Reactivity
Human
Applications
FC
Conjugate
Unconjugated
CloneNo.
TS2/4
验证数据展示
经过测试的应用
| Positive FC detected in | human PBMCs |
推荐稀释比
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
65527-1-PBS targets CD11a in FC applications and shows reactivity with Human samples.
| Tested Applications | FC Application Description |
| Tested Reactivity | Human |
| Immunogen | HLA-DR CTL line 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Recombinant |
| Type | Antibody |
| Full Name | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
| Synonyms | CD11A, Integrin alpha L, ITGAL, LFA 1, LFA 1A, LFA1A |
| Calculated Molecular Weight | 129 kDa |
| GenBank Accession Number | BC008777 |
| Gene Symbol | CD11a |
| Gene ID (NCBI) | 3683 |
| ENSEMBL Gene ID | ENSG00000005844 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Affinity purification |
| UNIPROT ID | P20701 |
| Storage Buffer | PBS only |
| Storage Conditions | Store at -80°C. Stable for one year after shipment. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CD11a antibody 65527-1-PBS | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
