验证数据展示
产品信息
66256-1-PBS targets CD11a/Integrin Alpha L in WB, IHC, IF/ICC, IF-P, ELISA applications and shows reactivity with human samples.
Tested Applications | WB, IHC, IF/ICC, IF-P, ELISA Application Description |
Tested Reactivity | human |
Immunogen | CD11a/Integrin Alpha L fusion protein Ag7813 种属同源性预测 |
Host / Isotype | Mouse / IgG1 |
Class | Monoclonal |
Type | Antibody |
Full Name | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) |
Synonyms | CD11a, ITGAL, Integrin alpha-L, Integrin alpha L, CD11 antigen-like family member A |
Calculated Molecular Weight | 129 kDa |
GenBank Accession Number | BC008777 |
Gene Symbol | CD11a |
Gene ID (NCBI) | 3683 |
ENSEMBL Gene ID | ENSG00000005844 |
RRID | AB_2881644 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
UNIPROT ID | P20701 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD11a, also known as integrin αL or LFA-1α, is a 170-180 kDa transmembrane glycoprotein that forms a heterodimer with CD18 (PMID: 7027264; 1672643). CD11a/CD18 (LFA-1) is expressed by all leukocytes and mediates cell adhesion through interactions with its ligands, intercellular adhesion molecule 1 (ICAM-1), ICAM-2, and ICAM-3 (PMID: 7479767). CD11a/CD18 also functions in lymphocyte costimulatory signaling (PMID: 1972160).