Anti-Rat CD11b (OX42)

CD11b Monoclonal Antibody for FC

Host / Isotype

Mouse / IgG2a, kappa

Reactivity

rat and More (1)

Applications

FC

Conjugate

Unconjugated

CloneNo.

OX42

Cat no : 65229-1-Ig

Print datasheet

Synonyms

OX42, Itgam, integrin alpha M



经过测试的应用

Positive FC detected inLOU rat splenocytes

推荐稀释比

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

65229-1-Ig targets CD11b in FC applications and shows reactivity with rat samples.

Tested Applications FC Application Description
Tested Reactivity rat
Cited Reactivitymouse
Immunogen Rat peritoneal macrophages 种属同源性预测
Host / Isotype Mouse / IgG2a, kappa
Class Monoclonal
Type Antibody
Full Name integrin alpha M
Synonyms OX42, Itgam, integrin alpha M
Calculated Molecular Weight127 kDa
GenBank Accession NumberNM_012711
Gene Symbol CD11b
Gene ID (NCBI) 25021
Conjugate Unconjugated
Form Liquid
Purification MethodAffinity purification
UNIPROT IDQ9JI30
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at 2-8°C. Stable for one year after shipment.

背景介绍

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).

实验方案

Product Specific Protocols
FC protocol for CD11b antibody 65229-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
mouseWB

Food Funct

Orally administered neohesperidin attenuates MPTP-induced neurodegeneration by inhibiting inflammatory responses and regulating intestinal flora in mice

Authors - Dewei He