Anti-Rat CD11b (OX42)
CD11b Monoclonal Antibody for FC
Host / Isotype
Mouse / IgG2a, kappa
Reactivity
rat and More (1)
Applications
FC
Conjugate
Unconjugated
CloneNo.
OX42
验证数据展示
经过测试的应用
Positive FC detected in | LOU rat splenocytes |
推荐稀释比
Application | Dilution |
---|---|
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
WB | See 1 publications below |
产品信息
65229-1-Ig targets CD11b in FC applications and shows reactivity with rat samples.
Tested Applications | FC Application Description |
Tested Reactivity | rat |
Cited Reactivity | mouse |
Immunogen | Rat peritoneal macrophages 种属同源性预测 |
Host / Isotype | Mouse / IgG2a, kappa |
Class | Monoclonal |
Type | Antibody |
Full Name | integrin alpha M |
Synonyms | OX42, Itgam, integrin alpha M |
Calculated Molecular Weight | 127 kDa |
GenBank Accession Number | NM_012711 |
Gene Symbol | CD11b |
Gene ID (NCBI) | 25021 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Affinity purification |
UNIPROT ID | Q9JI30 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).
实验方案
Product Specific Protocols | |
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FC protocol for CD11b antibody 65229-1-Ig | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Food Funct Orally administered neohesperidin attenuates MPTP-induced neurodegeneration by inhibiting inflammatory responses and regulating intestinal flora in mice |