Anti-Rat CD11b (OX42)
CD11b Monoclonal Antibody for FC
Host / Isotype
Mouse / IgG2a, kappa
Reactivity
rat and More (1)
Applications
FC
Conjugate
Unconjugated
CloneNo.
OX42
验证数据展示
经过测试的应用
| Positive FC detected in | LOU rat splenocytes |
推荐稀释比
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 1 publications below |
产品信息
65229-1-Ig targets CD11b in FC applications and shows reactivity with rat samples.
| Tested Applications | FC Application Description |
| Tested Reactivity | rat |
| Cited Reactivity | mouse |
| Immunogen | Rat peritoneal macrophages 种属同源性预测 |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | integrin alpha M |
| Synonyms | OX42, Itgam, integrin alpha M |
| Calculated Molecular Weight | 127 kDa |
| GenBank Accession Number | NM_012711 |
| Gene Symbol | CD11b |
| Gene ID (NCBI) | 25021 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Affinity purification |
| UNIPROT ID | Q9JI30 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at 2-8°C. Stable for one year after shipment. |
背景介绍
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11b, also known as Integrin alpha M or CR3A, belongs to the integrin alpha chain family. CD11b forms an α/β heterodimer with CD18 (integrin β2). CD11b/CD18 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles and pathogens (PMID: 9558116; 20008295). CD11b/CD18 is a receptor for the complement protein fragment iC3b, and is also a receptor for fibrinogen, factor X and ICAM1 (PMID: 2971974; 15485828).
实验方案
| Product Specific Protocols | |
|---|---|
| FC protocol for CD11b antibody 65229-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Food Funct Orally administered neohesperidin attenuates MPTP-induced neurodegeneration by inhibiting inflammatory responses and regulating intestinal flora in mice | ||
J Agric Food Chem Orally Administered Ginkgolide C Alleviates MPTP-Induced Neurodegeneration by Suppressing Neuroinflammation and Oxidative Stress through Microbiota-Gut-Brain Axis in Mice |
