CD122/IL2RB Monoclonal antibody, PBS Only
CD122/IL2RB Monoclonal Antibody for WB,Indirect ELISA
Host / Isotype
Mouse / IgG1
Reactivity
human
Applications
WB,Indirect ELISA
Conjugate
Unconjugated
CloneNo.
3A12C7
验证数据展示
产品信息
60174-1-PBS targets CD122/IL2RB in WB, Indirect ELISA applications and shows reactivity with human samples.
| Tested Applications | WB,Indirect ELISA Application Description |
| Tested Reactivity | human |
| Immunogen | CD122/IL2RB fusion protein Ag3929 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | interleukin 2 receptor, beta |
| Synonyms | CD122/IL2RB |
| Calculated Molecular Weight | 551 aa, 61 kDa |
| Observed Molecular Weight | 75 kDa, 61 kDa |
| GenBank Accession Number | BC025691 |
| Gene Symbol | IL2RB |
| Gene ID (NCBI) | 3560 |
| ENSEMBL Gene ID | ENSG00000100385 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P14784 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. |
背景介绍
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. The beta subunit (IL2RB, also known as CD122 and p75) is involved in receptor mediated endocytosis and transduces the mitogenic signals of nterleukin 2.
