CoraLite® Plus 488-conjugated CD133 Monoclonal antibody
CD133 Monoclonal Antibody for
Host / Isotype
Mouse / IgG1
Reactivity
Human and More (1)
Applications
Conjugate
CoraLite® Plus 488 Fluorescent Dye
CloneNo.
2B8A2
验证数据展示
For other applications, we recommend the unconjugated version of this antibody, 66666-1-Ig
产品信息
CL488-66666 targets CD133 in applications and shows reactivity with Human samples.
| Tested Applications | Application Description |
| Tested Reactivity | Human |
| Cited Reactivity | human |
| Immunogen | CD133 fusion protein Ag13327 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | prominin 1 |
| Synonyms | AC133, Antigen AC133, CD133, CORD12, MCDR2, MSTP061, PROM1, PROM1 1, PROM1 1,2,3, PROM1 1,2,3,5,7, PROM1 1,6,7, PROM1 2, PROM1 2,3,4,5, prominin 1, Prominin like protein 1, PROML1, RP41, STGD4 |
| Calculated Molecular Weight | 97 kDa |
| Observed Molecular Weight | 115 kDa, 80-90 kDa |
| GenBank Accession Number | BC012089 |
| Gene Symbol | CD133 |
| Gene ID (NCBI) | 8842 |
| Conjugate | CoraLite® Plus 488 Fluorescent Dye |
| Excitation/Emission Maxima Wavelengths | 493 nm / 522 nm |
| Form | Liquid |
| Purification Method | Protein G purification |
| UNIPROT ID | O43490 |
| Storage Buffer | PBS with 50% Glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3. |
| Storage Conditions | Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
CD133, also known as PROM1 (prominin-1) or AC133, belongs to the prominin family. CD133 is a transmembrane glycoprotein with an NH2-terminal extracellular domain, five transmembrane loops and a cytoplasmic tail. The expression of CD133 has been reported in hematopoietic stem cells, endothelial progenitor cells, neuronal and glial stem cells, suggesting the potential role of CD133 as a cell surface marker of adult stem cells. CD133 has also been reported as a marker of cancer stem cells in various human tumors. CD133 is a highly glycosylated protein with an apparent molecular weight of 115-120 kDa. After the treatment of the lysates with glycosidase, CD133 shifted to a protein with an apparent molecular weight of 80-90 kDa (PMID: 23150174; 20068153).
发表文章
| Species | Application | Title |
|---|---|---|
J Cancer Linc00662 sponges miR-15b-5p to promote hypopharyngeal squamous cell carcinoma progression by facilitating cancer stem cell-like phenotypes |
