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Anti-Human CD157 Rabbit Recombinant Antibody, PBS Only

CD157 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

241424H5

Cat no : 98146-1-PBS

Print datasheet

Synonyms

BST 1, Bone marrow stromal antigen 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, ADP-ribosyl cyclase 2, ADP ribosyl cyclase 2

验证数据展示

  • FC experiment of human peripheral blood leukocytes using 98146-1-RR (same clone as 98146-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98146-1-RR (same clone as 98146-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.15 ug Anti-Human CD157 Rabbit Recombinant Antibody (98146-1-RR, Clone: 241424H5), or Isotype Control and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed. This data was developed using the same antibody clone with 98146-1-PBS in a different storage buffer formulation.

  • FC experiment of human peripheral blood leukocytes using 98146-1-RR (same clone as 98146-1-PBS)

    FC experiment of human peripheral blood leukocytes using 98146-1-RR (same clone as 98146-1-PBS)

    1x10^6 human peripheral blood leukocytes were surface stained with 0.15 ug Anti-Human CD157 Rabbit Recombinant Antibody (98146-1-RR, Clone: 241424H5) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to fixing and staining. Cells were not fixed. This data was developed using the same antibody clone with 98146-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98146-1-RR

    Affinity and Kinetic Characterization of 98146-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98146-1-RR against Human CD157 were performed. The affinity constant is below 1 pM.

产品信息

98146-1-PBS targets CD157 in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Recombinant Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name bone marrow stromal cell antigen 1
Synonyms BST 1, Bone marrow stromal antigen 1, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2, ADP-ribosyl cyclase 2, ADP ribosyl cyclase 2
Calculated Molecular Weight 318 aa, 36 kDa
GenBank Accession NumberBC012095
Gene Symbol CD157
Gene ID (NCBI) 683
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ10588
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD157, also known as bone marrow stromal cell antigen 1 (BST-1), or ADP-ribosyl cyclase 2, is a glycosyl phosphotidylinositol-anchored protein that stimulates pre-B-cell growth and has adenosine diphosphate (ADP)-ribosyl cyclase and cyclic ADP-ribose (cADPR) hydrolase activity (PMID: 9473467, 11866528). The two enzymatic activities are responsible for the synthesis and hydrolysis of cADPR, a novel second messenger of calcium release from intracellular calcium stores.