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CD1c Polyclonal antibody

CD1c Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 28838-1-AP

Print datasheet

Synonyms

T-cell surface glycoprotein CD1c, R7, CD1c molecule, CD1, BDCA1

验证数据展示

  • IHC staining of human tonsillitis using 28838-1-AP

    IHC staining of human tonsillitis using 28838-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 28838-1-AP (CD1c antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human tonsillitis using 28838-1-AP

    IHC staining of human tonsillitis using 28838-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 28838-1-AP (CD1C antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

经过测试的应用

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

28838-1-AP targets CD1c in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen CD1c fusion protein Ag29830 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name CD1c molecule
Synonyms T-cell surface glycoprotein CD1c, R7, CD1c molecule, CD1, BDCA1
Calculated Molecular Weight 333 aa, 38 kDa
GenBank Accession NumberBC126467
Gene Symbol CD1C
Gene ID (NCBI) 911
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP29017
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CD1c molecule (CD1c, also known as R7, CD1, CD1A, and BDCA1) is a member of the CD1 family of transmembrane glycoproteins, which synthesizes in the endoplasmic reticulum and expresses on the monocytes, marginal zone B cells in lymph nodes as well as peripheral blood (PMID: 23468110). The CD1 proteins belong to the family of major histocompatibility complex (MHC) class I-like proteins that present lipid-based antigens to T cells (PMID: 15032598; 23127489). CD1c shows interaction with both αβ or γδ T cells and mediates T cell responses against mycobacterium tuberculosis (PMID: 10727456; 10786796).

实验方案

Product Specific Protocols
IHC protocol for CD1c antibody 28838-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols