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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 83437-5-RR (same clone as 83437-5-PBS)

    WB analysis using 83437-5-RR (same clone as 83437-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83437-5-RR (CD200 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83437-5-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 83437-5-RR (same clone as 83437-5-PBS)

    IHC staining of mouse brain using 83437-5-RR (same clone as 83437-5-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 83437-5-RR (CD200 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83437-5-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 83437-5-RR (same clone as 83437-5-PBS)

    IHC staining of mouse brain using 83437-5-RR (same clone as 83437-5-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 83437-5-RR (CD200 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83437-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83437-5-RR

    Affinity and Kinetic Characterization of 83437-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83437-5-RR against Mouse CD200 were performed. The affinity constant is 28.8 nM.

Mouse CD200 Recombinant antibody, PBS Only

CD200 Uni-rAbTM Recombinant Antibody for WB, IHC, ELISA
Cat No. 83437-5-PBS
CloneNo. 240391A8

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

WB, IHC, ELISA

Synonyms

OX2, Mox2, CD200 antigen, 240391A8

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -

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产品信息

83437-5-PBS targets CD200 in WB, IHC, ELISA applications and shows reactivity with mouse samples.

Tested Applications WB, IHC, ELISA Application Description
Tested Reactivity mouse
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD200 antigen
Synonyms OX2, Mox2, CD200 antigen, 240391A8
Calculated Molecular Weight31 kDa
Gene Symbol Cd200
Gene ID (NCBI) 17470
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO54901
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332).