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验证数据展示

  • FC experiment of human PBMCs using 98091-2-RR (same clone as 98091-2-PBS)

    FC experiment of human PBMCs using 98091-2-RR (same clone as 98091-2-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD200 Rabbit Recombinant Antibody (98091-2-RR, Clone: 241329G4) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD19 (4G7) Mouse IgG2a Recombinant Antibody (CL647-65562, Clone: 4G7). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98091-2-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 98091-2-RR (same clone as 98091-2-PBS)

    FC experiment of human PBMCs using 98091-2-RR (same clone as 98091-2-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD200 Rabbit Recombinant Antibody (98091-2-RR, Clone: 241329G4) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98091-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98091-2-RR

    Affinity and Kinetic Characterization of 98091-2-RR

    Biolayer interferometry (BLl) kinetic assays of 98091-2-RR against Human CD200 were performed. The affinity constant is 0.405 nM.

Anti-Human CD200 Rabbit Recombinant Antibody, PBS Only

CD200 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98091-2-PBS

产品说明书

CloneNo. 241329G4

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

FC

别名

OX 2, MRC, MOX2, MOX1, CD200 molecule

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98091-2-PBS targets CD200 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD200 molecule
别名 OX 2, MRC, MOX2, MOX1, CD200 molecule
计算分子量 269 aa, 30 kDa
GenBank蛋白编号BC022522
基因名称 CD200
Gene ID (NCBI) 4345
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP41217
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332).