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Anti-Mouse CD200R1 Rabbit Recombinant Antibody, PBS Only

CD200R1 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

FC

Conjugate

Unconjugated

CloneNo.

241453E7

Cat no : 98155-1-PBS

Print datasheet

Synonyms

OX2R, Mox2r, CD200R, CD200 receptor 1, 241453E7

验证数据展示

  • FC experiment of mouse bone marrow cells using 98155-1-RR (same clone as 98155-1-PBS)

    FC experiment of mouse bone marrow cells using 98155-1-RR (same clone as 98155-1-PBS)

    1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD200R1 Rabbit Recombinant Antibody (98155-1-RR, Clone: 241453E7) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98155-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse bone marrow cells using 98155-1-RR (same clone as 98155-1-PBS)

    FC experiment of mouse bone marrow cells using 98155-1-RR (same clone as 98155-1-PBS)

    1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD200R1 Rabbit Recombinant Antibody (98155-1-RR, Clone: 241453E7) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98155-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98155-1-RR

    Affinity and Kinetic Characterization of 98155-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98155-1-RR against Mouse CD200R1 were performed. The affinity constant is 3.33 nM.

产品信息

98155-1-PBS targets CD200R1 in FC applications and shows reactivity with mouse samples.

Tested Applications FC Application Description
Tested Reactivity mouse
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD200 receptor 1
Synonyms OX2R, Mox2r, CD200R, CD200 receptor 1, 241453E7
Calculated Molecular Weight36 kDa
GenBank Accession NumberNM_021325.3
Gene Symbol Cd200r1
Gene ID (NCBI) 57781
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ9ES57
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cell surface glycoprotein CD200 receptor 1 (CD200R1) is also called CD200R, CRTR2, MOX2R, and OX2R, and belongs to the CD200R family. CD200R1 is an inhibitory receptor for the CD200/OX2 cell surface glycoprotein. CD200R1 is highly glycosylated, containing ten potential N-glycosylation sites (PMID: 15187158). CD200R1 limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. As an immune inhibitory molecule, CD200R1 binds to CD200, ultimately leading to the inhibition of classical activation of macrophages and microglia (PMID: 24588829).