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Host
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Species Reactivity
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Species Reactivity
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验证数据展示

  • FC experiment of mouse bone marrow cells using 98155-1-RR (same clone as 98155-1-PBS)

    FC experiment of mouse bone marrow cells using 98155-1-RR (same clone as 98155-1-PBS)

    1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD200R1 Rabbit Recombinant Antibody (98155-1-RR, Clone: 241453E7) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98155-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse bone marrow cells using 98155-1-RR (same clone as 98155-1-PBS)

    FC experiment of mouse bone marrow cells using 98155-1-RR (same clone as 98155-1-PBS)

    1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD200R1 Rabbit Recombinant Antibody (98155-1-RR, Clone: 241453E7) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98155-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98155-1-RR

    Affinity and Kinetic Characterization of 98155-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98155-1-RR against Mouse CD200R1 were performed. The affinity constant is 3.33 nM.

Anti-Mouse CD200R1 Rabbit Recombinant Antibody, PBS Only

CD200R1 Uni-rAbTM Recombinant Antibody for FC
Cat No. 98155-1-PBS

产品说明书

CloneNo. 241453E7

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

OX2R, Mox2r, CD200R, CD200 receptor 1, 241453E7

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98155-1-PBS targets CD200R1 in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Fusion Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD200 receptor 1
别名 OX2R, Mox2r, CD200R, CD200 receptor 1, 241453E7
计算分子量36 kDa
GenBank蛋白编号NM_021325.3
基因名称 Cd200r1
Gene ID (NCBI) 57781
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDQ9ES57
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Cell surface glycoprotein CD200 receptor 1 (CD200R1) is also called CD200R, CRTR2, MOX2R, and OX2R, and belongs to the CD200R family. CD200R1 is an inhibitory receptor for the CD200/OX2 cell surface glycoprotein. CD200R1 is highly glycosylated, containing ten potential N-glycosylation sites (PMID: 15187158). CD200R1 limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. As an immune inhibitory molecule, CD200R1 binds to CD200, ultimately leading to the inhibition of classical activation of macrophages and microglia (PMID: 24588829).