Anti-Human CD206 (15-2)

CD206 Monoclonal Antibody for FC
Cat No. 65155-1-Ig

产品说明书

CloneNo. 15-2

宿主/亚型

Mouse / IgG1, kappa

种属反应性

Human

应用

FC

CD206, CLEC13D, Macrophage mannose receptor 1, mannose receptor, C type 1, MMR, MRC1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
规格: 

-/ -


经过测试的应用

Positive FC detected inhuman monocyte-derived dendritic cells
Planning an IHC experiment? We recommend our IHCeasy CD206 Ready-To-Use IHC Kit. CD206 primary antibody included.
Planning an IF experiment? We recommend our CoraLite® Plus 647 conjugated versions of this antibody.

推荐稀释比

应用推荐稀释比
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

65155-1-Ig targets CD206 in FC applications and shows reactivity with Human samples.

经测试应用 FC Application Description
经测试反应性 Human
免疫原 Purified human mannose receptor 种属同源性预测
宿主/亚型 Mouse / IgG1, kappa
抗体类别 Monoclonal
产品类型 Antibody
全称 mannose receptor, C type 1
别名 CD206, CLEC13D, Macrophage mannose receptor 1, mannose receptor, C type 1, MMR, MRC1
计算分子量 166 kDa
GenBank蛋白编号NM_002438
基因名称 CD206
Gene ID (NCBI) 4360
RRIDAB_2918437
偶联类型 Unconjugated
形式 Liquid
纯化方式Purified by protein-A affinity chromatography
UNIPROT IDP22897
储存缓冲液 PBS with 0.09% sodium azide , pH 7.3
储存条件Store at 2-8°C. Stable for one year after shipment.

背景介绍

CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.

实验方案

Product Specific Protocols
FC protocol for CD206 antibody 65155-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols
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