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CD206 Recombinant antibody, PBS Only

CD206 Recombinant Antibody for WB, IF, IHC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

Human, Pig, Mouse

Applications

WB, IF, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

1G15

Cat No : 81525-1-PBS

Print datasheet

Synonyms

CD206, CLEC13D, Macrophage mannose receptor 1, mannose receptor, C type 1, MMR, MRC1

验证数据展示

  • WB analysis using 81525-1-RR (same clone as 81525-1-PBS)

    WB analysis using 81525-1-RR (same clone as 81525-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 81525-1-RR (CD206 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 81525-1-PBS in a different storage buffer formulation.

  • IHC staining of human lung cancer using 81525-1-RR (same clone as 81525-1-PBS)

    IHC staining of human lung cancer using 81525-1-RR (same clone as 81525-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 81525-1-RR (CD206 antibody) at dilution of 1:2000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81525-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD206 antibody included
  • IHC staining of human lung cancer using 81525-1-RR (same clone as 81525-1-PBS)

    IHC staining of human lung cancer using 81525-1-RR (same clone as 81525-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 81525-1-RR (CD206 antibody) at dilution of 1:2000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81525-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD206 antibody included
  • IF Staining of human placenta using 81525-1-RR (same clone as 81525-1-PBS)

    IF Staining of human placenta using 81525-1-RR (same clone as 81525-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human placenta tissue using CD206 antibody (81525-1-RR, Clone: 1G15 ) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81525-1-PBS in a different storage buffer formulation.

  • IF Staining of human placenta using 81525-1-RR (same clone as 81525-1-PBS)

    IF Staining of human placenta using 81525-1-RR (same clone as 81525-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded human placenta tissue using CD206 antibody (81525-1-RR, Clone: 1G15 ) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 81525-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy CD206 Ready-To-Use IHC Kit. CD206 primary antibody included.

产品信息

81525-1-PBS targets CD206 in WB, IF, IHC, Indirect ELISA applications and shows reactivity with Human, Pig, Mouse samples.

Tested Applications WB, IF, IHC, Indirect ELISA Application Description
Tested Reactivity Human, Pig, Mouse
Immunogen Peptide 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name mannose receptor, C type 1
Synonyms CD206, CLEC13D, Macrophage mannose receptor 1, mannose receptor, C type 1, MMR, MRC1
Calculated Molecular Weight 166 kDa
Observed Molecular Weight170 kDa
GenBank Accession NumberNM_002438
Gene Symbol MRC1
Gene ID (NCBI) 4360
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP22897
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

CD206, also named as MMR, CLEC13D and MRC1, is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. CD206 has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. CD206 is a 170 kDa transmembrane protein which contains 5 domains: an amino-terminal cysteine-rich region, a fibronectin type II repeat, a series of eight tandem lectin-like carbohydrate recognition domains (responsible for the recognition of mannose and fucose), a transmembrane domain, and an intracellular carboxy-terminal tail. It is expressed on most tissue macrophages, in vitro derived dendritic cells, lymphatic and sinusoidal endothelia.