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CD209 Recombinant antibody, PBS Only

CD209 Uni-rAbTM Recombinant Antibody for WB, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

240907A2

Cat no : 84095-6-PBS

Print datasheet

Synonyms

DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN

验证数据展示

  • WB analysis of human placenta using 84095-6-RR (same clone as 84095-6-PBS)

    WB analysis of human placenta using 84095-6-RR (same clone as 84095-6-PBS)

    human placenta tissue was subjected to SDS PAGE followed by western blot with 84095-6-RR (CD209 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84095-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84095-6-RR

    Affinity and Kinetic Characterization of 84095-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84095-6-RR against Human CD209 were performed. The affinity constant is below 1 pM.

产品信息

The immunogen of 84095-6-PBS is CD209 Fusion Protein expressed in E. coli.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD209 molecule
Synonyms DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN
Calculated Molecular Weight 404 aa, 45.7 kDa
Observed Molecular Weight48 kDa
GenBank Accession NumberBC110615
Gene Symbol CD209
Gene ID (NCBI) 30835
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ9NNX6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).