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Anti-Human CD209 Rabbit Recombinant Antibody, PBS Only

CD209 Uni-rAbTM Recombinant Antibody for FC

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

240907A4

Cat no : 98156-1-PBS

Print datasheet

Synonyms

DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN

验证数据展示

  • FC experiment of human monocyte-derived immature dendritic cells using 98156-1-RR (same clone as 98156-1-PBS)

    FC experiment of human monocyte-derived immature dendritic cells using 98156-1-RR (same clone as 98156-1-PBS)

    1x10^6 human monocyte-derived immature dendritic cells were surface stained with 0.25 ug Anti-Human CD209 Rabbit Recombinant Antibody (98156-1-RR, Clone: 240907A4) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98156-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98156-1-RR

    Affinity and Kinetic Characterization of 98156-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98156-1-RR against Human CD209 were performed. The affinity constant is 1.94 nM.

产品信息

The immunogen of 98156-1-PBS is CD209 Fusion Protein expressed in E. coli.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD209 molecule
Synonyms DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN
Calculated Molecular Weight 404 aa, 45.7 kDa
GenBank Accession NumberBC110615
Gene Symbol CD209
Gene ID (NCBI) 30835
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ9NNX6
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).