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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 65573-1-MR (same clone as 65573-1-PBS)

    FC experiment of human PBMCs using 65573-1-MR (same clone as 65573-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD226 Mouse Recombinant Antibody (65573-1-MR, Clone: 11A8) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). Cells were co-stained with CoraLite® Plus 405 Anti-Human CD3. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65573-1-PBS in a different storage buffer formulation.

Anti-Human CD226 (11A8) Mouse IgG2a Recombinant Antibody, PBS Only

CD226 Uni-rAbTM Recombinant Antibody for FC
Cat No. 65573-1-PBS

产品说明书

CloneNo. 11A8

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC

别名

DNAM-1, DNAM1, DNAM 1, CD226 molecule, CD226 antigen

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

65573-1-PBS targets CD226 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 Human NK Cells 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 CD226 molecule
别名 DNAM-1, DNAM1, DNAM 1, CD226 molecule, CD226 antigen
计算分子量 336 aa, 39 kDa
GenBank蛋白编号BC074787
基因名称 CD226
Gene ID (NCBI) 10666
ENSEMBL Gene IDENSG00000150637
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C. Stable for one year after shipment.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).