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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 65627-1-MR (same clone as 65627-1-PBS)

    FC experiment of human PBMCs using 65627-1-MR (same clone as 65627-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD27 (O323) Mouse IgG2a Recombinant Antibody (65627-1-MR, Clone:O323) or 0.25 ug Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4), and PE-conjugated Goat Anti-Mouse IgG. Cells were then stained with APC Anti-Human CD3. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65627-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 65627-1-MR (same clone as 65627-1-PBS)

    FC experiment of human PBMCs using 65627-1-MR (same clone as 65627-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD27 (O323) Mouse IgG2a Recombinant Antibody (65627-1-MR, Clone: O323) (red) or 0.25 ug Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) (blue), and PE-conjugated Goat Anti-Mouse IgG. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65627-1-PBS in a different storage buffer formulation.

Anti-Human CD27 (O323) Mouse IgG2a Recombinant Antibody, PBS Only

CD27 Uni-rAbTM Recombinant Antibody for FC
Cat No. 65627-1-PBS

产品说明书

CloneNo. O323

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC

别名

CD27 antigen, CD27 molecule, CD27L receptor, S152, T cell activation antigen CD27

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

65627-1-PBS targets CD27 in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 N/A 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 CD27 molecule
别名 CD27 antigen, CD27 molecule, CD27L receptor, S152, T cell activation antigen CD27
计算分子量 29 kDa
GenBank蛋白编号BC012160
基因名称 CD27
Gene ID (NCBI) 939
ENSEMBL Gene IDENSG00000139193
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD27 (also known as TNFRSF7) is a type I glycoprotein expressed on some B cells and the majority of T cells, and is a member of the tumor necrosis factor (TNF) receptor family. CD27 is required for generation and long-term maintenance of T cell immunity (PMID: 11062504). It is a receptor for CD70 (CD27L). Ligation of CD27 by CD70 induces strong ubiquitination of TRAF and the activation of both canonical and non-canonical NF-kappaB pathways, as well as the JNK pathway (PMID: 19426224). CD27 may also play a role in apoptosis through association with SIVA1.