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Mouse CD31 Recombinant antibody, PBS Only

CD31 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

mouse

Applications

IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

242041E12

Cat no : 84607-4-PBS

Print datasheet

Synonyms

Pecam1, PECAM 1, Pecam, 242041E12

验证数据展示

  • IF Staining of bEnd.3 using 84607-4-RR (same clone as 84607-4-PBS)

    IF Staining of bEnd.3 using 84607-4-RR (same clone as 84607-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed bEnd.3 cells using CD31/PECAM-1 antibody (84607-4-RR, Clone: 242041E12 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84607-4-PBS in a different storage buffer formulation.

产品信息

84607-4-PBS targets CD31 in IF/ICC, Indirect ELISA applications and shows reactivity with mouse samples.

Tested Applications IF/ICC, Indirect ELISA Application Description
Tested Reactivity mouse
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name platelet/endothelial cell adhesion molecule 1
Synonyms Pecam1, PECAM 1, Pecam, 242041E12
Calculated Molecular Weight81 kDa
GenBank Accession NumberNM_001305157.1
Gene Symbol CD31
Gene ID (NCBI) 18613
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDQ08481-1
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) is a member of the immunoglobulin gene superfamily of cell adhesion molecules. CD31 is a transmembrane glycoprotein that is highly expressed on the surface of the endothelium, making up a large portion of its intracellular junctions. PECAM-1 is also present on the surface of hematopoietic cells and immune cells including platelets, monocytes, neutrophils, natural killer cells, megakaryocytes and some types of T-cell (PMID: 9011572). As well as its role in cell-cell adhesion, PECAM-1 functions as a signaling receptor, and is involved in important physiological events such as nitric oxide production, regulation of T-cell immunity and tolerance, leukocyte transendothelial migration and inflammation and angiogenesis (PMID: 21183735; 20978210; 17872453; 20634489).