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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of human PBMCs using 65643-1-MR (same clone as 65643-1-PBS)

    FC experiment of human PBMCs using 65643-1-MR (same clone as 65643-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD314/NKG2D (1D11) Mouse IgG2a Recombinant Antibody (65643-1-MR, Clone:1D11) or Mouse IgG2a Isotype Control, and PE-conjugated Goat Anti-Mouse IgG. Cells were co-stained with CoraLite® Plus 647 Anti-Human CD8 (UCHT4) Mouse IgG2a Recombinant Antibody. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65643-1-PBS in a different storage buffer formulation.

  • FC experiment of human PBMCs using 65643-1-MR (same clone as 65643-1-PBS)

    FC experiment of human PBMCs using 65643-1-MR (same clone as 65643-1-PBS)

    1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD314/NKG2D (1D11) Mouse IgG2a Recombinant Antibody (65643-1-MR, Clone:1D11) (red) or Mouse IgG2a Isotype Control (blue), and PE-conjugated Goat Anti-Mouse IgG. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 65643-1-PBS in a different storage buffer formulation.

Anti-Human CD314/NKG2D (1D11) Mouse IgG2a Recombinant Antibody, PBS Only

CD314/NKG2D Recombinant Antibody for FC
Cat No. 65643-1-PBS

产品说明书

CloneNo. 1D11

宿主/亚型

Mouse / IgG2a

种属反应性

human

应用

FC

别名

KLRK1, CD314, 1D11, KLR, Killer cell lectin-like receptor subfamily K member 1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

65643-1-PBS targets CD314/NKG2D in FC applications and shows reactivity with human samples.

经测试应用 FC Application Description
经测试反应性 human
免疫原 NKL cell line 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 killer cell lectin-like receptor subfamily K, member 1
别名 KLRK1, CD314, 1D11, KLR, Killer cell lectin-like receptor subfamily K member 1
计算分子量 25 kDa
GenBank蛋白编号BC039836
基因名称 KLRK1
Gene ID (NCBI) 22914
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In humans, it is expressed on NK cells, gamma delta T cells, and CD8+ alpha beta T cells (PMID: 10426993). Various families of cell surface ligands have been identified, including the MICA/MICB and ULBP proteins (PMID: 12150888). CD314 is involved in both innate and adaptive immunities, and the NKG2D/NKG2DL pathway involves multiple effector cell types for controlling tumor progression (PMID: 31720075).