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CD38 Recombinant antibody, PBS Only

CD38 Uni-rAbTM Recombinant Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

241246D5

Cat no : 84070-6-PBS

Print datasheet

Synonyms

ADPRC 1, ADP ribosyl cyclase 1, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase

验证数据展示

  • WB analysis using 84070-6-RR (same clone as 84070-6-PBS)

    WB analysis using 84070-6-RR (same clone as 84070-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84070-6-RR (CD38 antibody) at dilution of 1:17000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84070-6-PBS in a different storage buffer formulation.

  • IHC staining of human tonsillitis using 84070-6-RR (same clone as 84070-6-PBS)

    IHC staining of human tonsillitis using 84070-6-RR (same clone as 84070-6-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84070-6-RR (CD38 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84070-6-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD38 antibody included
  • IHC staining of human tonsillitis using 84070-6-RR (same clone as 84070-6-PBS)

    IHC staining of human tonsillitis using 84070-6-RR (same clone as 84070-6-PBS)

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84070-6-RR (CD38 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84070-6-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with CD38 antibody included
  • IF Staining of Raji using 84070-6-RR (same clone as 84070-6-PBS)

    IF Staining of Raji using 84070-6-RR (same clone as 84070-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Raji cells using CD38 antibody (84070-6-RR, Clone: 241246D5 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84070-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84070-6-RR

    Affinity and Kinetic Characterization of 84070-6-RR

    Biolayer interferometry (BLl) kinetic assays of 84070-6-RR against Human CD38 were performed. The affinity constant is 1.11 nM.

Planning an IHC experiment? We recommend our IHCeasy CD38 Ready-To-Use IHC Kit. CD38 primary antibody included.

产品信息

84070-6-PBS targets CD38 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human
Immunogen Fusion Protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD38 molecule
Synonyms ADPRC 1, ADP ribosyl cyclase 1, 2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-ADP-ribosyl cyclase
Calculated Molecular Weight 300 aa, 34 kDa
Observed Molecular Weight45 kDa
GenBank Accession NumberBC007964
Gene Symbol CD38
Gene ID (NCBI) 952
ENSEMBL Gene IDENSG00000004468
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDP28907
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).