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CD38 inhibitor 1

CD38 inhibitor 1 是一种有效的 CD38抑制剂，能够作用于人类的 CD38 (IC50:7.3 nM)和小鼠的 CD38 (IC50:1.9 nM)。

CAS号

1700637-55-3

分子式

C22H27N3O3S

主要靶点

CD38

仅限科研使用

Cat No : CM07886

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Synonyms

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  • CAS No.: 1700637-55-3

    CD38 inhibitor 1
    CAS#: 1700637-55-3

产品信息

CD38 inhibitor 1 is an inhibitor of CD38. For hCD38 and mouse CD38, the IC50s are 7.3 nM and 1.9 nM.

CAS号 1700637-55-3
分子式 C22H27N3O3S
主要靶点 CD38
主要通路 免疫与炎症
分子量 413.53
纯度 99.86%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名

靶点活性

CD38:1.9 nM(mouse)|CD38:7.3 nM(human)

体内活性

In liver and muscle, CD38 inhibitor (30 mg/kg; oral administration; 2 and 6 hours) obviously elevates NAD levels [1].

溶解度

DMSO:35.71 mg/mL (86.35 mM),Sonification is recommended.

参考文献

1.Haffner CD, et al. Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors. J Med Chem. 2015 Apr 23;58(8):3548-71.

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