Anti-Human CD4 (SK3), PBS Only
CD4 Monoclonal Antibody for Sandwich ELISA, Indirect ELISA
Host / Isotype
Mouse / IgG1, kappa
Reactivity
human
Applications
Sandwich ELISA, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
SK3
验证数据展示
产品信息
65147-1-PBS targets CD4 as part of a matched antibody pair:
MP50077-1: 65147-1-PBS capture and 68688-1-PBS detection (validated in Sandwich ELISA)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
Tested Applications | Sandwich ELISA, Indirect ELISA Application Description |
Tested Reactivity | human |
Immunogen | N/A 种属同源性预测 |
Host / Isotype | Mouse / IgG1, kappa |
Class | Monoclonal |
Type | Antibody |
Affinity | KD=8.82 x 10-11M KOff=2.00 x 10-5M KOn=2.26 x 105M |
Full Name | CD4 molecule |
Synonyms | T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, SK3, CD4mut, CD4 molecule |
Calculated Molecular Weight | 55 kDa |
GenBank Accession Number | BC025782 |
Gene Symbol | CD4 |
Gene ID (NCBI) | 920 |
ENSEMBL Gene ID | ENSG00000010610 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Affinity purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD4 is a 55-kDa transmembrane glycoprotein expressed on T helper cells, majority of thymocytes, monocytes, macrophages, and dendritic cells (PMID: 9304802; 12213222). CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It plays an important role in T helper cell development and activation (PMID: 9539765; 3112582). CD4 serves as a receptor for the human immunodeficiency virus (HIV) (PMID: 9304802).