验证数据展示
产品信息
65147-1-PBS targets CD4 as part of a matched antibody pair:
MP50077-1: 65147-1-PBS capture and 68688-1-PBS detection (validated in Sandwich ELISA)
Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.
This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.
经测试应用 | FC, Sandwich ELISA, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | N/A 种属同源性预测 |
宿主/亚型 | Mouse / IgG1, kappa |
抗体类别 | Monoclonal |
产品类型 | Antibody |
亲和力 | KD=8.82 x 10-11M KOff=2.00 x 10-5M KOn=2.26 x 105M |
全称 | CD4 molecule |
别名 | T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, SK3, CD4mut, CD4 molecule |
计算分子量 | 55 kDa |
GenBank蛋白编号 | BC025782 |
基因名称 | CD4 |
Gene ID (NCBI) | 920 |
ENSEMBL Gene ID | ENSG00000010610 |
RRID | AB_2918432 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Affinity purification |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD4 is a 55-kDa transmembrane glycoprotein expressed on T helper cells, majority of thymocytes, monocytes, macrophages, and dendritic cells (PMID: 9304802; 12213222). CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It plays an important role in T helper cell development and activation (PMID: 9539765; 3112582). CD4 serves as a receptor for the human immunodeficiency virus (HIV) (PMID: 9304802).