Anti-Human CD45RO (UCHL1), PBS Only

CD45RO Monoclonal Antibody for IHC, IF-P, FC
Cat No. 65150-1-PBS
CloneNo. UCHL1

Host / Isotype

Mouse / IgG2a, kappa

Reactivity

human

Applications

IHC, IF-P, FC

CD45, B220, LCA, L CA, GP180

Formulation:  PBS Only
PBS and Azide
PBS Only
Conjugate:  Unconjugated
Size: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy CD45 Ready-To-Use IHC Kit. CD45 primary antibody included.

产品信息

65150-1-PBS targets CD45RO in IHC, IF-P, FC applications and shows reactivity with human samples.

Tested Applications IHC, IF-P, FC Application Description
Tested Reactivity human
Immunogen IL-2 dependent T cell line, CA1 种属同源性预测
Host / Isotype Mouse / IgG2a, kappa
Class Monoclonal
Type Antibody
Full Name protein tyrosine phosphatase, receptor type, C
Synonyms CD45, B220, LCA, L CA, GP180
GenBank Accession NumberBC014239
Gene Symbol CD45
Gene ID (NCBI) 5788
ENSEMBL Gene IDENSG00000081237
RRIDAB_2881476
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP08575
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD45, also known as protein tyrosine phosphatase, receptor type C, is a type I transmembrane protein expressed on the surface of all haematopoietic cells with the exception of erythrocytes and platelets (PMID: 3489673; 28615666). CD45 is a pan-haematopoietic cell marker and has been shown to be essential for T- and B-cell activation and signalling (PMID: 9429890; 16378097). CD45 exists as multiple isoforms due to alternative splicing of three exons (4, 5, and 6, designated A, B, and C) in the extracellular domain (PMID: 12414720). CD45RO is the shortest CD45 isoform (lacking all three exons) and is expressed by activated and memory T cells, thymocytes, some B cells, and weakly on granulocytes and macrophage (PMID: 27100180; 12414720).

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