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Host
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Species Reactivity
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Species Reactivity
0
Conjugate
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Conjugate
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Compatible Species
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Conjugate
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验证数据展示

  • IHC staining of human prostate cancer using 20305-1-AP (same clone as 20305-1-PBS)

    IHC staining of human prostate cancer using 20305-1-AP (same clone as 20305-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 20305-1-AP (CD47 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20305-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 20305-1-AP (same clone as 20305-1-PBS)

    IHC staining of human prostate cancer using 20305-1-AP (same clone as 20305-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 20305-1-AP (CD47 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20305-1-PBS in a different storage buffer formulation.

CD47 Polyclonal antibody, PBS Only

CD47 Polyclonal Antibody for IHC, Indirect ELISA
Cat No. 20305-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

20305-1-PBS targets CD47 in IHC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 IHC, Indirect ELISA Application Description
经测试反应性 human
免疫原 CD47 fusion protein Ag14132 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 CD47 molecule
别名
计算分子量 323 aa, 35 kDa
GenBank蛋白编号BC010016
基因名称 CD47
Gene ID (NCBI) 961
RRIDAB_10732838
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ08722
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD47, also known as integrin-associated protein (IAP), is a member of the immunoglobulin superfamily containing a five-pass transmembrane attachment. CD47 is heavily glycosylated and widely expressed by hematopoietic and nonhematopoietic cells. CD47 interacts with several membrane integrins and also acts as a receptor for thrombospondin (THBS1). It is involved in a range of cellular processes, including apoptosis, proliferation, adhesion, and migration. CD47 also functions as a ligand for signal regulatory protein-α (SIRPα). Upon binding CD47, SIRPα initiates a signaling cascade that results in the inhibition of phagocytosis.