验证数据展示
产品信息
65609-1-PBS targets CD5 in FC applications and shows reactivity with human samples.
经测试应用 | FC Application Description |
经测试反应性 | human |
免疫原 | N/A 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | CD5 molecule |
别名 | T-cell surface glycoprotein CD5, T1, Lymphocyte antigen T1/Leu-1, Lymphocyte antigen T1/Leu 1, LEU1 |
计算分子量 | 495 aa, 55 kDa |
GenBank蛋白编号 | BC027901 |
基因名称 | CD5 |
Gene ID (NCBI) | 921 |
ENSEMBL Gene ID | ENSG00000110448 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD5 is a type I transmembrane glycoprotein of the scavenger receptor cysteine-rich family (PMID: 12403363). CD5 is expressed on a majority of thymocytes, mature T cells, B cell subsets, and peripheral blood dendritic cells (PMID: 9858516; 6156984; 10379049; 1384337). CD5 may act as a receptor in regulating T-cell proliferation. It functions as a negative regulator of TCR signaling during thymocyte development (PMID: 7542801).