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验证数据展示

  • IHC staining of human tonsillitis using 16763-1-AP

    IHC staining of human tonsillitis using 16763-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16763-1-AP (CD6 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human tonsillitis using 16763-1-AP

    IHC staining of human tonsillitis using 16763-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16763-1-AP (CD6 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human tonsillitis using 16763-1-AP

    IHC staining of human tonsillitis using 16763-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16763-1-AP (CD6 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human tonsillitis using 16763-1-AP

    IHC staining of human tonsillitis using 16763-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16763-1-AP (CD6 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

CD6 Polyclonal antibody

CD6 Polyclonal Antibody for IHC, ELISA
Cat No. 16763-1-AP

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IHC, ELISA

别名

TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  Unconjugated
Unconjugated
规格: 

-/ -

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经过测试的应用

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

应用推荐稀释比
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

16763-1-AP targets CD6 in IHC, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human
免疫原 CD6 fusion protein Ag10336 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 CD6 molecule
别名 TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule
计算分子量 668 aa, 72 kDa
GenBank蛋白编号BC078669
基因名称 CD6
Gene ID (NCBI) 923
RRIDAB_2878312
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDP30203
储存缓冲液 PBS with 0.02% sodium azide and 50% glycerol , pH 7.3
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CD6 is a type I transmembrane glycoprotein of 105-130 kDa that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harboring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands.

实验方案

Product Specific Protocols
IHC protocol for CD6 antibody 16763-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols