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CD6 Polyclonal antibody

CD6 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 16763-1-AP

Print datasheet

Synonyms

TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule

验证数据展示

  • IHC staining of human tonsillitis using 16763-1-AP

    IHC staining of human tonsillitis using 16763-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16763-1-AP (CD6 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human tonsillitis using 16763-1-AP

    IHC staining of human tonsillitis using 16763-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16763-1-AP (CD6 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human tonsillitis using 16763-1-AP

    IHC staining of human tonsillitis using 16763-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16763-1-AP (CD6 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human tonsillitis using 16763-1-AP

    IHC staining of human tonsillitis using 16763-1-AP

    Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 16763-1-AP (CD6 antibody) at dilution of 1:400 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

经过测试的应用

Positive IHC detected inhuman tonsillitis tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

16763-1-AP targets CD6 in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen CD6 fusion protein Ag10336 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name CD6 molecule
Synonyms TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule
Calculated Molecular Weight 668 aa, 72 kDa
GenBank Accession NumberBC078669
Gene Symbol CD6
Gene ID (NCBI) 923
RRIDAB_2878312
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP30203
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

CD6 is a type I transmembrane glycoprotein of 105-130 kDa that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harboring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands.

实验方案

Product Specific Protocols
IHC protocol for CD6 antibody 16763-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols