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CD6 Recombinant antibody, PBS Only (Detector)

CD6 Uni-rAbTM Recombinant Antibody for Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test

Conjugate

Unconjugated

CloneNo.

241965B11

Cat no : 84508-2-PBS

Print datasheet

Synonyms

TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule

验证数据展示

  • Sandwich ELISA standard curve of MP01358-2

    Sandwich ELISA standard curve of MP01358-2

    Sandwich ELISA standard curve of MP01358-2, Human CD6 Recombinant Matched Antibody Pair - PBS only. 84508-1-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Eg2079. 84508-2-PBS was HRP conjugated as the detection antibody. Range: 78.1-5000 pg/mL.

  • Sample test of MP01358-2

    Sample test of MP01358-2

    The mean CD6 concentration was determined to be 20.8 ng/mL in MOLT-4 cell extract based on a 1.2 mg/mL extract load and 10.9 ng/mL in Jurkat cell extract based on a 4.2 mg/mL extract load.

  • Sample test of MP01358-2

    Sample test of MP01358-2

    Serum of six individual healthy human donors was measured. The CD6 concentration of detected samples was determined to be 2,345.6 pg/mL with a range of 1,106.3-6,008.2 pg/mL.

  • Cytometric bead array standard curve of MP01358-2

    Cytometric bead array standard curve of MP01358-2

    Cytometric bead array standard curve of MP01358-2, CD6 Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84508-1-PBS. Detection antibody: 84508-2-PBS. Standard: Eg2079. Range: 0.781-100 ng/mL.

产品信息

84508-2-PBS targets CD6 as part of a matched antibody pair:

MP01358-2: 84508-1-PBS capture and 84508-2-PBS detection (validated in Cytometric bead array, Sandwich ELISA)

Unconjugated rabbit recombinant monoclonal antibody in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation. Created using Proteintech’s proprietary in-house recombinant technology. Recombinant production enables unrivalled batch-to-batch consistency, easy scale-up, and future security of supply.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

Tested Applications Cytometric bead array, Sandwich ELISA, Indirect ELISA, Sample test Application Description
Tested Reactivity human
Immunogen Recombinant protein 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name CD6 molecule
Synonyms TP120, T-cell differentiation antigen CD6, T12, Soluble CD6, CD6 molecule
GenBank Accession NumberBC033755
Gene Symbol CD6
Gene ID (NCBI) 923
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP30203
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD6 is a type I transmembrane glycoprotein of 105-130 kDa that belongs to the scavenger receptor cysteine-rich superfamily (PMID: 21880988). It is composed of an extracellular region, which consists of three tandem SRCR domains, a transmembrane region, and a cytoplasmic tail devoid of intrinsic catalytic activity but harbouring several phosphorylatable residues suitable for intracellular signal transduction (PMID: 38139340; 23711376). CD6 is expressed by T cells, medullary thymocytes, a subset of B cells and NK cells, and in some cells of the brain (PMID: 1919444; 21178331). CD6 plays a role in lymphocyte activation, proliferation, and survival processes via interaction with its endogenous ligands.