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Anti-Human CD62P (AK4) Mouse IgG2a Recombinant Antibody, PBS Only

CD62P Recombinant Antibody for FC

Host / Isotype

Mouse / IgG2a

Reactivity

human

Applications

FC

Conjugate

Unconjugated

CloneNo.

AK4

Cat no : 65587-1-PBS

Print datasheet

Synonyms

P-selectin, GMRP, GMP-140, GMP140, GMP 140

验证数据展示

  • FC experiment of human peripheral blood platelets using 65587-1-MR (same clone as 65587-1-PBS)

    FC experiment of human peripheral blood platelets using 65587-1-MR (same clone as 65587-1-PBS)

    1x10^6 thrombin treated human peripheral blood platelets were surface stained with 0.25 ug Anti-Human CD62P Mouse IgG2a Recombinant Antibody (65587-1-MR, Clone: AK4) (red) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) (blue) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L). Untreated human peripheral blood platelets were surface stained with 0.25 ug Anti-Human CD62P Mouse IgG2a Recombinant Antibody (65587-1-MR, Clone: AK4) and CoraLite®488-Conjugated AffiniPure Donkey Anti-Mouse IgG(H+L)(black). Cells were not fixed. This data was developed using the same antibody clone with 65587-1-PBS in a different storage buffer formulation.

产品信息

65587-1-PBS targets CD62P in FC applications and shows reactivity with human samples.

Tested Applications FC Application Description
Tested Reactivity human
Immunogen Human platelets 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Recombinant
Type Antibody
Full Name selectin P (granule membrane protein 140kDa, antigen CD62)
Synonyms P-selectin, GMRP, GMP-140, GMP140, GMP 140
Calculated Molecular Weight 830 aa, 91 kDa
GenBank Accession NumberBC028067
Gene Symbol CD62P
Gene ID (NCBI) 6403
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.