验证数据展示
产品信息
65605-1-PBS targets CD71 in FC applications and shows reactivity with human samples.
经测试应用 | FC Application Description |
经测试反应性 | human |
免疫原 | Human T-cell acute lymphoblastic leukemia cells 种属同源性预测 |
宿主/亚型 | Mouse / IgG2a |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | transferrin receptor (p90, CD71) |
别名 | TFR1, TFR, T9, sTfR, p90 |
计算分子量 | 85 kDa |
GenBank蛋白编号 | BC001188 |
基因名称 | CD71 |
Gene ID (NCBI) | 7037 |
ENSEMBL Gene ID | ENSG00000072274 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purification |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.