验证数据展示
产品信息
65605-1-PBS targets CD71 in FC applications and shows reactivity with human samples.
Tested Applications | FC Application Description |
Tested Reactivity | human |
Immunogen | Human T-cell acute lymphoblastic leukemia cells 种属同源性预测 |
Host / Isotype | Mouse / IgG2a |
Class | Recombinant |
Type | Antibody |
Full Name | transferrin receptor (p90, CD71) |
Synonyms | TFR1, TFR, T9, sTfR, p90 |
Calculated Molecular Weight | 85 kDa |
GenBank Accession Number | BC001188 |
Gene Symbol | CD71 |
Gene ID (NCBI) | 7037 |
ENSEMBL Gene ID | ENSG00000072274 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Protein A purification |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD71, also known as transferrin receptor protein 1 (TfR1), is a transmembrane glycoprotein composed of two disulfide-linked monomers, each of 90 kDa molecular weight. Each monomer binds one holo-transferrin molecule creating an iron-Tf-TfR complex that enters the cell by endocytosis. CD71 is present on actively proliferating cells and is essential for iron transport into proliferating cells.