CD79a Recombinant antibody, PBS Only
CD79a Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human
Applications
IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
1I17
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy CD79a Ready-To-Use IHC Kit. CD79a primary antibody included.
产品信息
82747-2-PBS targets CD79a in IF/ICC, Indirect ELISA applications and shows reactivity with human samples.
| Tested Applications | IF/ICC, Indirect ELISA Application Description |
| Tested Reactivity | human |
| Immunogen | CD79a fusion protein Ag17924 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | CD79a molecule, immunoglobulin-associated alpha |
| Synonyms | MB 1, Ig-alpha, IGA, Ig alpha, B-cell antigen receptor complex-associated protein alpha chain |
| Calculated Molecular Weight | 226 aa, 25 kDa |
| GenBank Accession Number | BC113733 |
| Gene Symbol | CD79A |
| Gene ID (NCBI) | 973 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P11912 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
CD79a, also named as B-cell antigen receptor complex-associated protein alpha chain or MB-1 membrane glycoprotein, is a 226 amino acid protein, which contains one ITAM domain and one Ig-like C2-type (immunoglobulin-like) domain. CD79A is expressed in B cells and localizes in the cell membrane. CD79A is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79A is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.