• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • WB analysis using 84236-5-RR (same clone as 84236-5-PBS)

    WB analysis using 84236-5-RR (same clone as 84236-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84236-5-RR (CD79a antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84236-5-PBS in a different storage buffer formulation.

  • IF Staining of Ramos using 84236-5-RR (same clone as 84236-5-PBS)

    IF Staining of Ramos using 84236-5-RR (same clone as 84236-5-PBS)

    Immunofluorescent analysis of (4% PFA) fixed Ramos cells using CD79A antibody (84236-5-RR, Clone: 241299C9 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84236-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84236-5-RR

    Affinity and Kinetic Characterization of 84236-5-RR

    Biolayer interferometry (BLl) kinetic assays of 84236-5-RR against Human CD79a were performed. The affinity constant is 3.77 nM.

CD79a Recombinant antibody, PBS Only

CD79a Uni-rAbTM Recombinant Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 84236-5-PBS

产品说明书

CloneNo. 241299C9

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IF/ICC, Indirect ELISA

别名

MB 1, Ig-alpha, IGA, Ig alpha, B-cell antigen receptor complex-associated protein alpha chain

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

点击咨询售前客服

点击咨询售后客服

Planning an IHC experiment? We recommend our IHCeasy CD79a Ready-To-Use IHC Kit. CD79a primary antibody included.

产品信息

84236-5-PBS targets CD79a in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human
免疫原 Recombinant Protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 CD79a molecule, immunoglobulin-associated alpha
别名 MB 1, Ig-alpha, IGA, Ig alpha, B-cell antigen receptor complex-associated protein alpha chain
计算分子量 226 aa, 25 kDa
观测分子量40-45 kDa
GenBank蛋白编号BC113733
基因名称 CD79A
Gene ID (NCBI) 973
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP11912
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD79a, also named as B-cell antigen receptor complex-associated protein alpha chain or MB-1 membrane glycoprotein, is a 226 amino acid protein, which contains one ITAM domain and one Ig-like C2-type (immunoglobulin-like) domain. CD79A is expressed in B cells and localizes in the cell membrane. CD79A is required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. CD79A is also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells.