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Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • FC experiment of rat splenocytes using 65577-1-MR (same clone as 65577-1-PBS)

    FC experiment of rat splenocytes using 65577-1-MR (same clone as 65577-1-PBS)

    1x10^6 rat splenocytes were surface stained with 0.25 ug Anti-Rat CD8a Mouse IgG2a Recombinant Antibody (65577-1-MR, Clone: OX-8) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) and FITC anti-Mouse IgG2a Antibody. Cells were then stained with APC Anti-Rat CD4. Cells were not fixed. This data was developed using the same antibody clone with 65577-1-PBS in a different storage buffer formulation.

  • FC experiment of rat splenocytes using 65577-1-MR (same clone as 65577-1-PBS)

    FC experiment of rat splenocytes using 65577-1-MR (same clone as 65577-1-PBS)

    1x10^6 rat splenocytes were surface stained with 0.25 ug Anti-Rat CD8 Mouse IgG2a Recombinant Antibody (65577-1-MR, Clone:OX-8) (red) or Mouse IgG2a Isotype Control (65208-1-Ig, Clone: C1.18.4) (blue) and FITC anti-Mouse IgG2a Antibody. Cells were not fixed. This data was developed using the same antibody clone with 65577-1-PBS in a different storage buffer formulation.

Anti-Rat CD8 (OX-8) Mouse IgG2a Recombinant Antibody, PBS Only

CD8 Recombinant Antibody for FC
Cat No. 65577-1-PBS

产品说明书

CloneNo. OX-8

宿主/亚型

Mouse / IgG2a

种属反应性

rat

应用

FC

别名

Cd8a, OX-8, CD8a molecule

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

65577-1-PBS targets CD8 in FC applications and shows reactivity with rat samples.

经测试应用 FC Application Description
经测试反应性 rat
免疫原 N/A 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Recombinant
产品类型 Antibody
全称 CD8a molecule
别名 Cd8a, OX-8, CD8a molecule
GenBank蛋白编号BC088126
基因名称 Cd8a
Gene ID (NCBI) 24930
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CD8 is a transmembrane glycoprotein composed of two disulfide-linked chains. It can be present as a homodimer of CD8α or as a heterodimer of CD8α and CD8β (PMID: 3264320; 8253791). CD8 is found on most thymocytes. The majority of class I-restricted T cells express mostly the CD8αβ heterodimer while CD8αα homodimers alone have been found on some gut intraepithelial T cells , on some T cell receptor (TCR) γδ T cells and on NK cells (PMID: 2111591; 1831127; 8420975). CD8 acts as a co-receptor that binds to MHC class-I and participates in cytotoxic T cell activation (PMID: 8499079). During T cell development, CD8 is required for positive selection of CD4-/CD8+ T cells (PMID: 1968084).