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CDC25B-IN-1

CDC25B-IN-1 是 CDC25B 的抑制剂，Ki 为 8.5 μM。 CDC25B-IN-1 通过抑制细胞增殖和集落形成来增加 G2/M 期。

CAS号

2374831-10-2

分子式

C20H19NO3

主要靶点

Phosphatase

仅限科研使用

Cat No : CM14490

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Synonyms

ethyl 3-[(3-methoxynaphthalen-1-yl)amino]benzoate

验证数据展示

  • CAS No.: 2374831-10-2

    CDC25B-IN-1
    CAS#: 2374831-10-2

产品信息

CDC25B-IN-1 is an inhibitor of CDC25B with a Ki of 8.5 μM. CDC25B-IN-1 increases the G2/M phase by inhibiting cell proliferation and colony formation.

CAS号 2374831-10-2
分子式 C20H19NO3
主要靶点 Phosphatase
主要通路 代谢
分子量 321.37
纯度 97.86%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 ethyl 3-[(3-methoxynaphthalen-1-yl)amino]benzoate

靶点活性

CDC25B phosphatase(ki):ki： 8.5 μM

溶解度

DMSO:90 mg/mL (280.1 mM),Sonification is recommended.

参考文献

1.Cerchia C, et al. Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism, and in Vitro Efficacy against Melanoma Cell Lines. J Med Chem. 2019 Aug 8;62(15):7089-7110.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2