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Species Reactivity
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验证数据展示

  • WB analysis using 66420-1-Ig (same clone as 66420-1-PBS)

    WB analysis using 66420-1-Ig (same clone as 66420-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66420-1-Ig (CDC37 Antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66420-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 66420-1-Ig (same clone as 66420-1-PBS)

    IF Staining of HeLa using 66420-1-Ig (same clone as 66420-1-PBS)

    Immunofluorescent analysis of (-20℃ Ethanol ) fixed HeLa cells using 66420-1-Ig(CDC37 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66420-1-PBS in a different storage buffer formulation.

CDC37 Monoclonal antibody, PBS Only

CDC37 Monoclonal Antibody for WB, IF/ICC, Indirect ELISA
Cat No. 66420-1-PBS

产品说明书

CloneNo. 1C2A6

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse, rat

应用

WB, IF/ICC, Indirect ELISA

别名

CDC37, CDC37A, Hsp90 co chaperone Cdc37, P50CDC37

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy CDC37 Ready-To-Use IHC Kit. CDC37 primary antibody included.

产品信息

66420-1-PBS targets CDC37 in WB, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 CDC37 fusion protein Ag0267 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 cell division cycle 37 homolog (S. cerevisiae)
别名 CDC37, CDC37A, Hsp90 co chaperone Cdc37, P50CDC37
计算分子量 44 kDa
观测分子量 44 kDa
GenBank蛋白编号BC000083
基因名称 CDC37
Gene ID (NCBI) 11140
RRIDAB_2881792
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ16543
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CDC(cell division control) family of proteins are regulatory proteins involved in the processes of cell cycle and proliferation. CDC37, migrated as a protein of 50 kDa in SDS PAGE, is a co-chaperone protein that recruits several immature client kinases to Hsp90 for proper folding. It functions in association with Hsp90, although little is known of its mechanism of action or where it fits into a folding pathway involving other Hsp90 cochaperones. CDC37 up-regulation is a common early event in some localized human cancers. But, the effect of CDC37 dysregulation in human cells is unclear.