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CDC37 Monoclonal antibody, PBS Only

CDC37 Monoclonal Antibody for WB,Indirect ELISA,IF

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat

Applications

WB,Indirect ELISA,IF

Conjugate

Unconjugated

CloneNo.

1C2A6

Cat No : 66420-1-PBS

Print datasheet

Synonyms

CDC37, CDC37A, Hsp90 co chaperone Cdc37, P50CDC37

验证数据展示

  • WB analysis using 66420-1-Ig (same clone as 66420-1-PBS)

    WB analysis using 66420-1-Ig (same clone as 66420-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66420-1-Ig (CDC37 Antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66420-1-PBS in a different storage buffer formulation.

  • IF Staining of HeLa using 66420-1-Ig (same clone as 66420-1-PBS)

    IF Staining of HeLa using 66420-1-Ig (same clone as 66420-1-PBS)

    Immunofluorescent analysis of (-20℃ Ethanol ) fixed HeLa cells using 66420-1-Ig(CDC37 antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66420-1-PBS in a different storage buffer formulation.

产品信息

66420-1-PBS targets CDC37 in WB, IF, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB,Indirect ELISA,IF Application Description
Tested Reactivity human, mouse, rat
Immunogen CDC37 fusion protein Ag0267 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name cell division cycle 37 homolog (S. cerevisiae)
Synonyms CDC37, CDC37A, Hsp90 co chaperone Cdc37, P50CDC37
Calculated Molecular Weight 44 kDa
Observed Molecular Weight 44 kDa
GenBank Accession NumberBC000083
Gene Symbol CDC37
Gene ID (NCBI) 11140
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ16543
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

CDC(cell division control) family of proteins are regulatory proteins involved in the processes of cell cycle and proliferation. CDC37, migrated as a protein of 50 kDa in SDS PAGE, is a co-chaperone protein that recruits several immature client kinases to Hsp90 for proper folding. It functions in association with Hsp90, although little is known of its mechanism of action or where it fits into a folding pathway involving other Hsp90 cochaperones. CDC37 up-regulation is a common early event in some localized human cancers. But, the effect of CDC37 dysregulation in human cells is unclear.