验证数据展示
经过测试的应用
Positive IP detected in | HeLa cells |
推荐稀释比
应用 | 推荐稀释比 |
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Immunoprecipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
WB | See 6 publications below |
产品信息
12877-1-AP targets p15 INK4b in WB, IP, ELISA applications and shows reactivity with human samples.
经测试应用 | IP, ELISA Application Description |
文献引用应用 | WB |
经测试反应性 | human |
文献引用反应性 | human, mouse |
免疫原 | p15 INK4b fusion protein Ag3557 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) |
别名 | MTS2, CDKN2B, p14 INK4b, MTS-2, MTS 2 |
计算分子量 | 138 aa, 15 kDa |
GenBank蛋白编号 | BC014469 |
基因名称 | p15 INK4b/CDKN2B |
Gene ID (NCBI) | 1030 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P42772 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
实验方案
Product Specific Protocols | |
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IP protocol for p15 INK4b antibody 12877-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Oncogene CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A. | ||
EMBO Rep MYC promotes cancer progression by modulating m6 A modifications to suppress target gene translation. | ||
Cell Cycle Cell proliferation downregulated by TGF-β2-triggered G1/S checkpoint in clinical CAFs. | ||
Pancreatology Smad4 deficiency substitutes Cdkn2b but not Cdkn2a downregulation in pancreatic cancer following induction of genetic events in adult mice. | ||
PLoS One NRF2-regulated cell cycle arrest at early stage of oxidative stress response mechanism. | ||
Dis Model Mech A novel pancreatic cancer model originated from transformation of acinar cells in adult tree shrew, a primate-like animal. |