验证数据展示
产品信息
10421-1-PBS targets CEA/CD66e in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | WB, IHC, IF-P, Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | CEA/CD66e fusion protein Ag0672 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | carcinoembryonic antigen-related cell adhesion molecule 5 |
别名 | |
计算分子量 | 77 kDa |
观测分子量 | 180-200 kDa, 77 kDa |
GenBank蛋白编号 | BC034671 |
基因名称 | CEA |
Gene ID (NCBI) | 1048 |
RRID | AB_2244691 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P06731 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Carcinoembryonic antigen (CEA), also known as CEACAM5 or CD66e, is a cell surface glycoprotein belonging to the immunoglobulin superfamily, mainly serving as a cell adhesion molecule mediating intercellular contact by both homophilic and heterophilic binding (PMID: 21731662). CEA inhibits anoikis and plays a role in tumorigenesis and metastasis. CEA has been found to be overexpressed in a wide variety of human cancers, including colon, breast, and lung (PMID: 17167768). CEA is a tumor marker and is routinely exploited for diagnosis.