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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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验证数据展示

  • FC experiment of mouse splenocytes using 98185-1-RR (same clone as 98185-1-PBS)

    FC experiment of mouse splenocytes using 98185-1-RR (same clone as 98185-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CEACAM1/CD66a Rabbit Recombinant Antibody (98185-1-RR, Clone: 241856H5) or 0.25 ug Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD45R. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98185-1-PBS in a different storage buffer formulation.

  • FC experiment of mouse splenocytes using 98185-1-RR (same clone as 98185-1-PBS)

    FC experiment of mouse splenocytes using 98185-1-RR (same clone as 98185-1-PBS)

    1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CEACAM1/CD66a Rabbit Recombinant Antibody (98185-1-RR, Clone: 241856H5) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD45R. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98185-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 98185-1-RR

    Affinity and Kinetic Characterization of 98185-1-RR

    Biolayer interferometry (BLl) kinetic assays of 98185-1-RR against Mouse CEACAM1/CD66a were performed. The affinity constant is below 1 pM.

Anti-Mouse CEACAM1/CD66a Rabbit Recombinant Antibody, PBS Only

CEACAM1/CD66a Uni-rAbTM Recombinant Antibody for FC
Cat No. 98185-1-PBS

产品说明书

CloneNo. 241856H5

宿主/亚型

Rabbit / IgG

种属反应性

mouse

应用

FC

别名

Biliary glycoprotein D, Biliary glycoprotein 1, BGP-1, Bgp1, Bgp

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

98185-1-PBS targets CEACAM1/CD66a in FC applications and shows reactivity with mouse samples.

经测试应用 FC Application Description
经测试反应性 mouse
免疫原 Recombinant protein 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 carcinoembryonic antigen-related cell adhesion molecule 1
别名 Biliary glycoprotein D, Biliary glycoprotein 1, BGP-1, Bgp1, Bgp
计算分子量57 kDa
基因名称 Ceacam1
Gene ID (NCBI) 26365
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purfication
UNIPROT IDP31809-1
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

CEACAM1, also known as CD66a or BGP (biliary glycoprotein), is a member of the cacinoembryonic antigen (CEA) family which belongs to the immunoglobulin superfamily of cell adhesion molecules (PMID: 16919437). CEACAMs play major roles in cell-cell and cell-ECM adhesion and have been implicated in the control of cell proliferation, angiogenesis, and tissue remodeling (PMID: 23021083). CEACAM1 is a transmembrane glycoprotein that is expressed on epithelial, endothelial, and immune cells (PMID: 30314283). CEACAM1 has been demonstrated to play a role in morphogenesis, apoptosis, angiogenesis, cell proliferation, cell motility, fibrosis, and immunity (PMID: 31604530).